[1] Mercer TR, Dinger ME, Mattick JS.Long non-coding RNAs:insights into functions[J]. Nat Rev Genet, 2009, 10(3):155-159. DOI:10.1038/nrg2521.
[2] Anderson DM, Anderson KM, Chang CL, et al. A micropeptide encoded by a putative long non-coding RNA regulates muscle performance[J]. Cell, 2015, 160(4):595-606. DOI:10.1016/j.cell.2015.01.009.
[3] Wilusz JE, Sunwoo H, Spector DL.Long noncoding RNAs:functional surprises from the RNA world[J]. Genes Dev, 2009, 23(13):1494-1504. DOI:10.1101/gad.1800909.
[4] Ponting CP, Oliver PL, Reik W. Evolution and functions of long noncoding RNAs[J]. Cell, 2009, 136(4):629-641. DOI:10.1016/j.cell.2009.02.006.
[5] Ransohoff JD, Wei Y, Khavari PA. The functions and unique features of long intergenic non-coding RNA[J]. Nat Rev Mol Cell Biol, 2018, 19(3):143-157. DOI:10.1038/nrm.2017.104.
[6] Smith MA, Gesell T, Stadler PF, et al. Widespread purifying selection on RNA structure in mammals[J]. Nucleic Acids Res, 2013, 41(17):8220-8236. DOI:10.1093/nar/gkt596.
[7] Melissari MT, Grote P. Roles for long non-coding RNAs in physiology and disease[J]. Pflugers Arch, 2016, 468(6):945-958. DOI:10.1007/s00424-016-1804-y.
[8] Guttman M, Amit I, Garber M, et al. Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals[J]. Nature, 2009, 458(7235):223-227. DOI:10.1038/nature07672.
[9] Chen LL, Carmichael GG. Long noncodin g RNAs in mammalian cells:what, where, and why?[J]. Wiley Interdiscip Rev RNA, 2010, 1(1):2-21. DOI:10.1002/wrna.5.
[10] Mchugh CA, Chen CK, Chow A, et al. The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3[J].Nature, 2015, 521(7551):232-236. DOI:10.1038/nature14443.
[11] Zhou JC, Yang LH, Zhong TY, et al. H19 lncRNA alters DNA methylation genome wide by regulating S-adenosylhomocysteine hydrolase[J]. Nat Commun, 2015, 6:10221. DOI:10.1038/ncomms 10221.
[12] Huang YP, Zheng YF, Jin CY, et al. Long non-coding RNA H19 inhibits adipocyte differentiation of bone marrow mesenchymal stem cells through epigenetic modulation of histone deacetylases[J]. Sci Rep, 2016, 628(6):28897. DOI:10.1038/srep28897.

Morris KV, Sharon S, Turner AM, et al. Bidirectional transcription directs both transcriptional gene activation and suppression in human cells[J/OL]. PLoS Genet, 2008, 4(11): e1000258[2018-01-20].http://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1000258&type=printable. DOI: 10.1371/journal.pgen.1000258.

[14] Martens JA, Laprade L, Winston F. Intergenic transcription is required to repress the Saccharomyces cerevisiae SER3 gene[J]. Nature, 2004, 429(6991):571-574. DOI:10.1038/nature02538.
[15] Tripathi V, Ellis JD, Shen Z, et al.The nuclear-retained noncoding RNA MALAT1 regulates alternative splicing by modulating SR splicing factor phosphorylation[J]. Mol Cell, 2010, 39(6):925-938.DOI:10.1016/j.molcel.2010.08.011.
[16] Hirose T, Virnicchi G, Tanigawa A, et al. NEAT1 long noncoding RNA regulates transcription via protein sequestration within subnuclear bodies[J]. Mol Biol Cell, 2014, 25(1):169-183. DOI:10.1091/mbc.E13-09-0558.
[17] Angrand PO, Vennin C, Le Bourhis XL. The role of long non-coding RNAs in genome formatting and expression[J]. Front Genet, 2015, 429(6):165. DOI:10.3389/fgene.2015.00165.
[18] Deckbar D, Jeggo PA, Löbrich M.Understanding the limitations of radiation-induced cell cycle checkpoints[J]. Crit Rev Biochem Mol Biol, 2011, 46(4):271-283. DOI:10.3109/10409238. 2011.575764.
[19] Warmerdam DO, Kanaar R. Dealing with DNA damage:Relationships between checkpoint and repair pathways[J]. Mutat Res, 2010, 704(1/3):2-11. DOI:10.1016/j.mrrev.2009.12.001.
[20] Liu X, Li D, Zhang W, et al. Long non-coding RNA gadd7 interacts with TDP-43 and regulates Cdk6 mRNA decay[J]. EMBO J, 2012, 31(23):4415-4427. DOI:10.1038/emboj.2012.292.
[21] Wang X, Arai S, Song X, et al. Induced ncRNAs allosterically modify RNA-binding proteins in cis to inhibit transcription[J]. Nature, 2008, 454(720):126-130. DOI:10.1038/nature06992.
[22] Zhang M, Gao C, Yang Y, et al. Long noncoding RNA CRNDE/PRC2 participated in the radiotherapy resistance of human lung adenocarcinoma through targeting p21 expression[J]. Oncol Res, 2017. DOI:10.3727/096504017X14944585873668.
[23] Jiang Y, Li Y, Fang S, et al. The role of MALAT1 correlates with HPV in cervical cancer[J]. Oncol Lett, 2014, 7(6):2135-2141. DOI:10.3892/ol.2014.1996.
[24] Wang J, Su L, Chen X, et al. MALAT1 promotes cell proliferation in gastric cancer by recruiting SF2/ASF[J]. Biomed Pharmacother, 2014, 68(5):557-564. DOI:10.1016/j.biopha.2014.04.007.
[25] Lu H, He Y, Lin L, et al.Long non-coding RNA MALAT1 modulates radiosensitivity of HR-HPV+ cervical cancer via sponging miR-145[J]. Tumour Biol, 2016, 37(2):1683-1691. DOI:10.1007/s13277-015-3946-5.
[26] Prensner JR, Chen W, Iyer MK, et al. PCAT-1, a long noncoding RNA, regulates BRCA2 and controls homologous recombination in cancer[J]. Cancer Res, 2014, 74(6):1651-1660. DOI:10.1158/0008-5472. CAN-13-3159.
[27] Zhang Y, He Q, Hu Z, et al. Long noncoding RNA LINP1 regulates double strand DNA break repair in triple negative breast cancer[J].Nat Struct Mol Biol, 2016, 23(6):522-530. DOI:10.1038/nsmb.3211.
[28] Sharma V, Khurana S, Kubben N, et al. A BRCA1-interacting lncRNA regulates homologous recombination[J]. EMBO Rep, 2015, 16(11):1520-1534. DOI:10.15252/embr.201540437.
[29] Wan G, Hu X, Liu Y, et al. A novel non-coding RNA lncRNA-JADE connects DNA damage signalling to histone H4 acetylation[J]. EMBO J, 2013, 32(21):2833-2847. DOI:10.1038/emboj.2013.221.
[30] Wang G, Li Z, Zhao Q, et al. LincRNA-p21 enhances the sensitivity of radiotherapy for human colorectal cancer by targeting the Wnt/β-catenin signaling pathway[J]. Oncol Rep, 2014, 31(4):1839-1845. DOI:10.3892/or.2014.3047.
[31] Shen Y, Liu Y, Sun T, et al. LincRNA-p21 knockdown enhances radiosensitivity of hypoxic tumor cells by reducing autophagy through HIF-1/Akt/mTOR/P70S6K pathway[J]. Exp Cell Res, 2017, 358(2):188-198. DOI:10.1016/j.yexcr.2017.06.016.
[32] Wan GH, Mathur R, Hu XX, et al. Long non-coding RNA ANRIL (CDKN2B-AS) is induced by the ATM-E2F1 signaling pathway[J].Cell Signal, 2013, 25(5):1086-1095. DOI:10.1016/j.cellsig.2013. 02.006.
[33] Hu XG, Jiang HJ, Jiang XJ. Downregulation of lncRNA ANRIL inhibits proliferation, induces apoptosis, and enhances radiosensitivity in nasopharyngeal carcinoma cells through regulating miR-125a[J]. Cancer Biol Ther, 2017, 18(5):331-338.DOI:10.1080/15384047.2017.1310348.
[34] Hung T, Wang Y, Lin MF, et al. Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters[J]. Nat Genet, 2011, 43(7):621-629. DOI:10.1038/ng.848.
[35] O'leary VB, Ovsepian SV, Carrascosa LG, et al. PARTICLE, a triplex-forming long ncRNA, regulates locus-specific methylation in response to low-dose irradiation[J]. Cell Rep, 2015, 11(3):474-485. DOI:10.1016/j.celrep.2015.03.043.
[36] Tan JM, Qiu KF, Li MY, et al. Double-negative feedback loop between long non-coding RNA TUG1 and miR-145 promotes epithelial to mesenchymal transition and radioresistance in human bladder cancer cells[J]. FEBS Lett, 2015, 589(20 Pt B):3175-3181.DOI:10.1016/j.febslet.2015.08.020.